Every marker we offer, grouped by body system. Open any marker for a summary, or go to its group page for the guideline behind it, the ranges, what can affect it and what we do if it's out of range. We count each result once and show calculated scores separately.
Medically reviewed by Anantha Chentha, MD, Co-Founder and Chief Quality Medical Officer · October 30, 2026. Meet our cliniciansNext review: October 2027
In Full Blood WorkFocused panel or single testCalculated
01
Heart & vascular
Cholesterol particles and inherited risk that guidelines use to decide on prevention.
Counts the particles that carry cholesterol into artery walls.
Why it matters: Each LDL, VLDL and IDL particle carries one ApoB, so ApoB counts the particles that can lodge in artery walls. The 2026 ACC/AHA dyslipidemia guideline uses ApoB to refine risk and to guide treatment, especially with diabetes, high triglycerides or a low LDL.
Ranges: Goals in the 2026 ACC/AHA guideline: under 90, 70 or 55 mg/dL depending on your overall risk.
What can affect it: Diet, weight, insulin resistance, thyroid function and cholesterol medicines.
If it’s out of range: Weighed with your 10-year risk; a lifestyle plan and, when appropriate, medicine.
When to retest: 8–12 weeks after a diet or medicine change.
An inherited cholesterol particle; one test in adulthood is usually enough.
Why it matters: Lp(a) is set mainly by your genes and changes little over life. The 2026 ACC/AHA guideline and the National Lipid Association recommend measuring it at least once in every adult.
Ranges: 125 nmol/L (about 50 mg/dL) or higher raises heart attack and stroke risk about 1.4-fold; 250 nmol/L (about 100 mg/dL) or higher about 2-fold (ACC/AHA 2026).
What can affect it: Mostly genetics. Kidney disease and menopause can raise it.
If it’s out of range: A high level lowers the threshold for treating other risk factors; close relatives may want testing.
Why it matters: LDL is the main treatment target in the 2026 ACC/AHA dyslipidemia guideline, with goals of under 100, 70 or 55 mg/dL depending on your risk. In the standard panel it is calculated from the other three lipid results.
Ranges: Below 100 mg/dL is considered optimal; 190 mg/dL or higher usually warrants treatment.
What can affect it: Diet, weight, genetics, thyroid function and medicines.
If it’s out of range: Combined with blood pressure and age to estimate 10-year risk and set a goal.
When to retest: 4–12 weeks after starting or changing a statin.
HDL cholesterol
In Full Blood Work
Cholesterol carried away from the arteries.
Why it matters: Used in heart-risk calculators. Raising HDL with medicine has not been shown to prevent heart attacks.
Ranges: Low below 40 mg/dL in men and below 50 mg/dL in women.
What can affect it: Exercise, weight, smoking and genetics.
If it’s out of range: Considered in your overall risk estimate.
When to retest: With your next lipid panel.
Triglycerides
In Full Blood Work
Blood fats that rise with sugar, alcohol and weight.
Why it matters: Persistently elevated triglycerides (175 mg/dL or more) are a risk-enhancing factor in ACC/AHA cholesterol guidelines.
Ranges: 150 mg/dL or higher is elevated; 500 or higher needs prompt treatment.
What can affect it: Recent meals, alcohol, blood sugar, weight and some medicines.
If it’s out of range: A nutrition plan; very high levels are treated promptly to protect the pancreas.
When to retest: 8–12 weeks after changes.
Total cholesterol
In Full Blood Work
All cholesterol combined.
Why it matters: Used with HDL in heart-risk calculators.
Ranges: Below 200 mg/dL is desirable.
What can affect it: Diet, genetics and medicines.
If it’s out of range: Read together with LDL, HDL and ApoB.
When to retest: With your next lipid panel.
Non-HDL cholesterol
Calculated
Total cholesterol minus HDL: cholesterol in harmful particles.
Why it matters: A secondary treatment target, especially useful when triglycerides are high.
Ranges: Goal is usually 30 mg/dL above your LDL goal.
What can affect it: Same as LDL and triglycerides.
If it’s out of range: Shown on your report, not counted as a separate test.
When to retest: With your lipid panel.
02
Inflammation
Low-grade inflammation that adds to heart risk.
1 marker · 1 in the Full Blood Work
Get these in
High-sensitivity CRP
In Full Blood Work
Low-grade inflammation linked to heart disease.
Why it matters: ACC/AHA cholesterol guidelines treat hs-CRP of 2.0 mg/L or more as a risk-enhancing factor.
Ranges: 2.0 mg/L or higher is risk-enhancing; above 10 suggests an acute illness.
What can affect it: Infections, injuries, arthritis flares, weight and smoking.
If it’s out of range: A very high result is repeated after you recover.
When to retest: 2–3 weeks after an illness if it was high.
Why it matters: The most useful single blood test for your iron stores.
Ranges: Below 45 ng/mL points to iron deficiency when anemia is present (AGA 2020); below 15 confirms it in healthy adults (WHO 2020). Inflammation can raise ferritin.
What can affect it: Inflammation, liver disease and iron supplements.
If it’s out of range: Low iron gets a cause work-up and treatment.
Blood Work